Carlo Calissano,Nicholas Chiorazzi,Rajendra N. Damle,Piers Patten
申请号：
US13377514
公开号：
US20120128586A1
申请日:
2010.06.24
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention provides a method for treating a subject having chronic lymphocytic leukemia (CLL) comprising administering to the subject one or more agents that target cell surface membrane antigens expressed preferentially on cells of the proliferative compartment of a CLL clone of the subject to treat chronic lymphocytic leukemia in the subject. The present invention also provides a method for treating a subject having chronic lymphocytic leukemia comprising administering to the subject one or more agents that target cell surface membrane antigens expressed preferentially on cells of the “resting re-entry compartment” to treat chronic lymphocytic leukemia in the subject.
