Calicheamicin-antibody-drug conjugates and methods of use

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专利权人:

Genentech; Inc.

发明人:

Thomas Pillow

申请号：

US16444326

公开号：

US10730900B2

申请日:

2019.06.18

申请国别(地区):

US

年份:

2020

代理人:

摘要：

The invention relates generally to a calicheamicin molecule activated with a leaving group. The invention further relates generally to an antibody-drug conjugate comprising an antibody directly conjugated by a disulfide to one or more calicheamicin molecules.

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中国工程科技知识中心

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http://www.ckcest.cn/home/