GERHARD RENNER,HANS BÄR,MICHAEL GOTTSCHALK,THOMAS FÜRST,THOMAS RUPP
申请号：
BRPI0924427
公开号：
BRPI0924427A2
申请日:
2009.03.18
申请国别(地区):
BR
年份:
2016
代理人:
摘要：
The invention relates to a controlled release pharmaceutical composition, comprising a core, comprising a pharmaceutical active ingredient, whereby the core is coated by an ethanol resistance conferring coating layer which has the effect of conferring the release profile of the pharmaceutical active ingredient to be resistant against the influence of ethanol. The coating layer comprises a polymeric portion consisting of a water-insoluble neutral vinyl polymer or vinyl copolymer and an amino methacrylate copolymer and an excipients portion consisting of a lubricant, an emulsifier, a plasticizer and optionally a cellulosic compound.
