A hand-held personalized measured dosing inhalation device having one or more cartridges containing vaporizable-liquid, one or more corresponding atomizers configured to vaporize the liquid so as to be inhaled by a user, a micro controller configured to monitor and regulate the vaporization process at one or more of the cartridges, and one or more external biometric sensors configured to be in communication with the controller, wherein the controller regulates vaporization of the liquid only upon authorization conveyed by the biometric sensors and when predetermined conditions are satisfied, the authorization condition being partially determined by input signaling received from internal sensors coupled to the cartridges and/or outlet.