Michel DEMEULE,Sasmita TRIPATHY,Alain LAROCQUE,Joanne Catherine MCGREGOR
申请号:
US14896258
公开号:
US20160367691A1
申请日:
2014.06.06
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention is related to the one-step synthesis of enzyme conjugates and methods for treating or preventing MPS-II by administering such conjugates. In certain embodiments, these compounds can cross the blood-brain barrier or accumulate in the lysosome more effectively than the enzyme alone.