ALEC D. LEBSACK,ANNE E. FITZGERALD,JING LIU,JOHN M. KEITH,KELLY J. MCCLURE,MARK D. ROSEN,MICHAEL D. HACK,NATALIE A. HAWRYLUK,NEELAKANDHA S. MANI,PAUL KRAWCZUK,STEVEN P. MEDUNA,WENDY ECCLES,WILLIAM M.
申请号：
BR112015018504
公开号：
BR112015018504A2
申请日:
2014.01.31
申请国别(地区):
BR
年份:
2017
代理人:
摘要：
abstract the present invention relates to compounds of formula (i), (i) or a form thereof, wherein ring a, r1, l and r2 are as defined herein, useful as flap modulators. the invention also relates to pharmaceutical compositions comprising compounds of formula (i). methods of making and using the compounds of formula (i) are also within the scope of the invention. Flap Modulators. The present invention relates to compounds of formula (i), (i) or a form thereof, wherein ring a, r1, l and r2 are as defined herein, useful as flap modulators. The invention also relates to pharmaceutical compositions comprising compounds of formula (I). Methods of manufacture and use of the compounds of formula (I) are also within the scope of the invention.abstract the present invention relates to compounds of formula (i), (i) or a form thereof, wherein ring a, r1, l and r2 are as defined herein, useful as flap modulators. the invention also relates to pharmaceutical compositions comprising compounds of formula (i). methods of making and using the compounds of formula (i) are also within the scope of the invention. tradução do resumo resumo patente de invenção "moduladores de flap". a presente invenção refere-se a compostos da fórmula (i), (i) ou uma forma dos mesmos, em que o anel a, r1, l e r2 são conforme definidos no presente documento, úteis como moduladores de flap. a invenção também se refere a composições farmacêuticas que compreendem compostos da fórmula (i). os métodos de fabricação e o uso dos compostos da fórmula (i) também estão dentro do escopo da invenção.
