CRYSTALS AND ACID MANUFACTURING PROCESS 5 - ({[2-AMINO-3- (4-CARBAMOYL-2,6-DIMETHYL-PHENYL) -PROPIONYL] - [1- (4-PHENYL-1H-IMIDAZOL-2-IL ) -ETIL] -AMINO} -METIL) -2-BENZOIC METOXY

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专利权人:

JANSSEN PHARMACEUTICA N.V.

发明人:

LUIGI ANZALONE,FRANK J. VILLANI,CHRISTOPHER ALLAN TELEHA,PENINA FEIBUSH,BARRY FEGELY

申请号：

BRPI0813632

公开号：

BRPI0813632A2

申请日:

2008.07.07

申请国别(地区):

BR

年份:

2014

代理人:

摘要：

The present invention relates to a novel crystals of 5-({[2-amino-3-(4-carbamoyl-2,6-dimethyl-phenyl)-propionyl]-[1-(4-phenyl-1h-imidazol-2-yl)-ethyl]-amino}-methyl)-2-methoxy-benzoic acid and methods of making the zwitterion of 5-({[2-amino-3-(4-carbamoyl-2,6-dimethyl-phenyl)-propionyl]-[1-(4-phenyl-1h-imidazol-2-yl)-ethyl]-amino}-methyl)-2-methoxy-benzoic acid.

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