PROBLEM TO BE SOLVED: To provide studies for promoting the proliferation of hair horny cells that are the most important in the production of hair roots and for inducing a differentiation to the hair, and to provide methods of utilizing a series of growth factors that supply a nutrient to around the hair and promote the activity of vascular endothelial growth factor.SOLUTION: A peptide exhibiting the activity of WNT protein is characterized by being derived from human WNT protein, by consisting of specific amino acid sequences, and by having N terminal to which a protecting group selected from the group consisting of an acetyl group, a fluorenyl methoxycarbonyl group, a formyl group, a palmitoyl, a myristyl group, a stearyl group, and polyethyleneglycol (PEG) is bound.SELECTED DRAWING: None【課題】毛根の生成において最も重要な毛髪の角質細胞の増殖を促進し、毛髪への分化を誘導するための研究、及び毛髪周囲に栄養分を供給し、血管内皮増殖因子の活性を促進させる一連の成長因子の活用法の提供。【解決手段】ヒトＷＮＴタンパク質から由来し、特定のアミノ酸配列からなり、Ｎ末端は、アセチル基、フルオレニルメトキシカルボニル基、ホルミル基、パルミトイル基、ミリスチル基、ステアリル基及びポリエチレングリコール（ＰＥＧ）から構成された群より選択される保護基が結合されていることを特徴とするＷＮＴタンパク質の活性を示すペプチド。【選択図】なし
