University of Pittsburgh—Of the Commonwealth System of Higher Education
发明人:
Nick Giannoukakis,Massimo M. Trucco
申请号：
US14546755
公开号：
US09724365B2
申请日:
2014.11.18
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention relates to tolerogenic mammalian dendritic cells (iDCs) and methods for the production of tolerogenic DCs. In addition, the present invention provides methods for administration of tolerogenic dendritic cells as well as particles containing oligonucleotides to mammalian subjects. Enhanced tolerogenicity in a host can be useful for treating inflammatory and autoimmune related diseases, such as type 1 diabetes.
