CONDON, STEPHEN M.,DENG, YIJUN,LAPORTE, MATTHEW G.,RIPPIN, SUSAN R.
申请号：
PE2012000215
公开号：
PE20131173A1
申请日:
2010.06.25
申请国别(地区):
PE
年份:
2013
代理人:
摘要：
Refers to an isomerized formula compound (I), wherein R5 is - ch2ch3, or a pharmaceutically acceptable salt. The most popular compounds are n - {1s - [2R - (6,6 '- difluorotriene' - {4s-hydroxi-1 - [2S - (2s-methylamine-propionalimino) - butiril] - pirrolidin-2r-ilmeth} - 1H, 1'h - [2,2 '] biolil-3-ilmethyl -- 4s-hydroxi-pirrolidin-1-carbon] - propil} - 2s-methylamine-midiona. These compounds are useful in the treatment of diffuse disordersREFERIDA A UN COMPUESTO HETEROCICLICO DE FORMULA (I), DONDE R5 ES -CH2CH3 O UNA SAL FARMACEUTICAMENTE ACEPTABLE DEL MISMO. UN COMPUESTO FAVORITO ES N-{1S-[2R-(6,6'-DIFLUORO-3'-{4S-HIDROXI-1-[2S-(2S-METILAMINO-PROPIONILAMINO)-BUTIRIL]-PIRROLIDIN-2R-ILMETIL}-1H,1'H-[2,2']BIINDOLIL-3-ILMETIL)-4S-HIDROXI-PIRROLIDIN-1-CARBONIL]-PROPIL}-2S-METILAMINO-PROPIONAMIDA. DICHOS COMPUESTOS SON UTILES EN EL TRATAMIENTO DE UN TRASTORNO PROLIFERATIVO
