University Health Network;The Hospital For Sick Children
发明人:
WANG, C. Y. JEAN,DICK, JOHN,DANSKA, JAYNE,JIN, LIQING,THEOCHARIDES, ALEXANDRE,RAJAKUMAR, SUJEETHA
申请号:
PL10774475
公开号:
PL2429574T3
申请日:
2010.05.14
申请国别(地区):
PL
年份:
2015
代理人:
摘要:
The invention relates to modulating the SIRP±-CD47 interaction in order to treat haematological cancer and compounds therefor. In some embodiments, there is provided methods and uses of SIRP± polypeptides, fragments and fusion proteins for treating haematological cancer, preferably human acute myeloid leukemia.