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PROCESS FOR THE PREPARATION OF PIPERAZINYL AND DIAZEPANYL BENZAMIDE DERIVATIVES
专利权人:
JANSSEN PHARMACEUTICA N.V.
发明人:
CHOUDHURY, ANUSUYA,GRIMM, JEFFREY S
申请号:
NZ57760307
公开号:
NZ577603A
申请日:
2007.12.10
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Disclosed is a process for the preparation of formula (Ia) or a pharmaceutically acceptable salt, ester, tautomer, solvate or amide thereof, wherein reacting a compound of formula (Xa) with a compound of formula (XIa) in the presence of a peptide coupling agent, in an organic solvent or mixture of organic solvents, to yield the corresponding compound of formula (Ia). Further disclosed is a process for the preparation of formula (Ib) or a pharmaceutically acceptable salt, ester, tautomer, solvate or amide thereof, wherein reacting a compound of formula (Xb) with a compound of formula (XIb) in the presence of a peptide coupling agent, in an organic solvent or mixture of organic solvents, to yield the corresponding compound of formula (Ib).
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