CHIANG JIA LI,HARRY ROGOFF,YOUZHI LI,JI-FENG LIU,WEI LI
申请号:
PT08829600
公开号:
PT2197878T
申请日:
2008.09.05
申请国别(地区):
PT
年份:
2016
代理人:
摘要:
The present invention relates to novel thiazole-substituted indolin-2-ones as inhibitors of CSCPK and related kinases to methods of inhibiting cancer stem cells by using a kinase inhibitor to pharmaceutical compositions containing such compounds and to methods of using such compounds in the treatment of protein kinase related disorder in a mammal and to processes of making such compounds and intermediates thereof.