4-[9-chloro-7-(2-fluoro-6-metoxifenil) -5 h-pirimido [5.4-d] [2] benzazepin-2-il] amine}-2-methoxyformic acid, containing at least 15% propylene glycol, 15% egg400 and less than 50% water in the solvent; and the preparation of a P drug To treat cancer.
RAMANAN VIJAYALAKSHMI,TOBIAS IRENE SOPHIE,VERWIJS DAUNTEL SPECHT,SKWIERCZYNSKI RAYMOND D.
申请号:
CL2012000261
公开号:
CL2012000261A1
申请日:
2012.01.31
申请国别(地区):
CL
年份:
2012
代理人:
摘要:
Pharmaceutical composition comprising acid 4 - {[- 7 - 9 - chlorine (2-fluoro-6 - (4-methoxyphenyl) 5h - 5.4 - pirimido [d] [2] benzazepin] amino} - 2 (IL - 2 - metoxibenzoico, solventA buffer solution and excipients such as preservatives and Surfactants; Process for producing a Pharmaceutical Form; and a method for treating cancer.<;p>;Composició;n farmacé;utica que comprende á;cido 4-{[9-cloro-7-(2-fluoro-6-metoxifenil)-5h-pirimido[5,4-d][2]benzazepin-2-il]amino}-2-metoxibenzoico, un disolvente, una solució;n amortiguadora y excipientes tales como conservantes y agentes tensioactivos; proceso para producir una forma farmacé;utica; y mé;todo para tratar el cá;ncer.<;/p>;