TURUNEN, JANNE JUHA,AALTO, ANTTI,KLEIN, BART,VAN SINT FIET, LENKA,BOUDET, JULIEN AUGUSTE GERMAIN
申请号:
CA3035293
公开号:
CA3035293A1
申请日:
2017.08.31
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
The invention relates to antisense oligonucleotides that are capable of bringing about specific editing of a target nucleotide (adenosine) in a target RNA sequence in a eukaryotic cell, wherein said oligonucleotide does not, in itself, form an intramolecular hairpin or stem-loop structure, and wherein said oligonucleotide comprises a non-complementary nucleotide in a position opposite to the nucleotide to be edited in the target RNA sequence.