医薬成分が長期安定化された経口投与医薬ゼリー製剤

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专利权人:

大蔵製薬株式会社

发明人:

菱川 慶裕,垣野 由佳理

申请号：

JP2009021141

公开号：

JP5320091B2

申请日:

2009.02.02

申请国别(地区):

JP

年份:

2013

代理人:

摘要：

PROBLEM TO BE SOLVED: To provide an orally administrable jelly pharmaceutical formulation which has features as a jelly formulation such as taste masking effect, easiness in taking (fluidity), and easiness in carrying, in which a pharmaceutical ingredient made unstable by the presence of previously contained water and/or an amorphized pharmaceutical ingredient are stabilized over a long period of time, and which does not need complicated operations such as extemporaneous preparation at the time of taking.

SOLUTION: A pharmaceutical ingredient made unstable by the presence of water and/or an amorphized pharmaceutical ingredient are once dissolved or suspended in a fat and oil, and the resultant solution or suspension is included in microcapsules. The microcapsules are mixed and formulated with a jelly agent to prepare an orally administrable jelly pharmaceutical formulation in which the pharmaceutical ingredients are stabilized over a long period of time and which does not need complicated operations such as extemporaneous preparation at the time of taking.

COPYRIGHT: (C)2010,JPO&INPIT

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