HALL, ADRIAN,FARTHING, CHRISTOPHER NEIL,CASTRO PINEIRO, JOSE LUIS
申请号：
CA2828738
公开号：
CA2828738A1
申请日:
2012.01.20
申请国别(地区):
CA
年份:
2012
代理人:
摘要：
The present invention relates to a fused aminodihydrothiazine derivative of formula (I): wherein X is hydrogen or fluorine； A is CH or N； Y is methyl, ethyl, monofluoromethyl, difluoromethyl, trifluoromethyl, difluoroethyl, methoxy, ethoxy, methoxymethyl or -C=N； and pharmaceutically acceptable salts thereof； which compound has an ?ß production inhibitory effect or a BACEl inhibitory effect and is useful as a prophylactic or therapeutic agent for a neurodegenerative disease caused by ?ß and typified by Alzheimer-type dementia.
