GEGE, CHRISTIAN,STEENECK, CHRISTOPH,KINZEL, OLAF,KLEYMANN, GERALD,HOFFMANN, THOMAS
申请号:
SG11201407919W
公开号:
SG11201407919WA
申请日:
2013.05.29
申请国别(地区):
SG
年份:
2014
代理人:
摘要:
The invention provides modulators for the orphan nuclear receptor RORy and methods for treating RORy mediated diseases by administering these novel RORy modulators to a human or a mammal in need thereof. Specifically, the present invention provides carboxamide or sulfonamide containing cyclic compounds of Formula (1), (1′), (100), (100′), (200) and (200′) and the enantiomers, diastereomers, tautomers, /V-oxides, solvates and pharmaceutically acceptable salts thereof.