Joel Plumas;Caroline Aspord;Laurence Chaperot-Dubonnet
发明人:
Joel Plumas,Caroline Aspord,Laurence Chaperot-Dubonnet
申请号：
US12993076
公开号：
US20120020998A1
申请日:
2009.05.15
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention relates to a method for inducing and amplifying specific effectors, which comprises obtaining pulsed plasmacytoid dendritic cells (pDC) by incubation of a pDC line with at least one antigen, the pulsed pDC being subsequently irradiated and brought into contact with peripheral blood mononuclear cells (PBMC), and cultured or injected into an organism. The pulsed and irradiated pDC and the PBMC share at least one major histocompatibility complex (MHC) allele.
