WONG, OI KWAN,CHOU, JOYCE CHING,SASU, BARBRA JOHNSON
申请号:
CA2954802
公开号:
CA2954802A1
申请日:
2017.01.12
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The present invention provides antibodies that specifically bind to EGFRvIII(Epidermal Growth Factor Receptor Variant III). The invention further providesbispecific antibodies that bind to EGFRvIII and another antigen (e.g., CD3) aswell asantibody conjugates (e.g., antibody-drug-conjugates). The invention furtherrelates toantibody encoding nucleic acids, and methods of obtaining such antibodies(monospecific and bispecific) and antibody conjugates.