Provided are lyophilized formulations comprising pegylated arginine deiminase (ADI-PEG) and related reconstituted liquid compositions and methods of using the compositions for arginine depletion therapies, including for the treatment of various cancers.提供包含聚乙二醇化精胺酸脫亞胺酶(ADI-PEG)及相關經復原液體組成物之凍乾調配物,及使用該組成物以進行精胺酸耗盡療法(包括治療各種癌症)之方法。