DIMETHOXY DOCETAXEL ACETONE SOLVATE ET METHOD FOR THE PREPARATION THEREOF

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专利权人:

AVENTIS PHARMA S.A.

发明人:

DIDIER ERIC,DIDIER Eric,PERRIN MARC-ANTOINE,PERRIN Marc-Antoine

申请号：

SI200432016

公开号：

SI1667986T1

申请日:

2004.09.16

申请国别(地区):

SI

年份:

2013

代理人:

摘要：

The acetone solvate (A) of 4-acetoxy-2alpha -benzoyloxy-5beta ,20-epoxy-1-hydroxy-7beta ,10beta -dimethoxy-9-oxo-tax-11-en-13alpha -yl (2R,3S)-3-tert. butoxycarbonylamino-2-hydroxy-3-phenylpropionate (I) (i.e. dimethoxy docetaxel) (preferably containing 5-7 wt. % acetone) is new. An independent claim is included for the preparation of (A). ACTIVITY : Cytostatic. MECHANISM OF ACTION : None given in the source material.

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