The present invention involves a cleaning sleeve for cleaning the oral cavity, suitable to be applied over a finger or a tool to clean the inside of the oral cavity. The cleaning sleeve has a flat-layered structure comprising a sleeve portion (1) formed by laminated sheet-like fabrics and a grip portion (2) formed by a single-layer sheet-like fabric, wherein the sleeve portion (1) comprises a working layer (11) and a sleeve layer (12); the working layer (11) and the sleeve layer (12) form a head (13) at the top of the cleaning sleeve; and the grip portion (2) is integrally extended from the working layer (11). The cleaning sleeve is formed by ultrasonically bonding the two sides of a piece of folded degradable nonwoven fabric. Since additional processes such as sewing and connecting are not required for the two, the cleaning sleeve is easy in mass manufacturing, low in cost and therefore suitable for disposable use. The general public can afford to use the cleaning sleeves on a daily basis with low prices. In addition, the thermal bonding effect and the water locking property of the degradable nonwoven fabric achieve a perfect balance.