NOUVEAUX ACCEPTEURS DE FLUORURE DE SILICIUM HETEROAROMATIQUES POUR MARQUAGE 18F DE MOLECULES ET DE BIOMOLECULES, ET PROCEDES DE PREPARATION CORRESPONDANTS
CALIFORNIA INSTITUTE OF TECHNOLOGY;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
发明人:
WALDMANN, CHRISTOPHER MARTIN,TOUTOV, ANTON A.,MURPHY, JENNIFER MARIE,GRUBBS, ROBERT H.
申请号:
CA2982269
公开号:
CA2982269A1
申请日:
2016.05.24
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The present invention includes novel compounds and compositions including heteroaromatic Silicon-Fluoride- Acceptors, which are useful for PET scanning. The present invention further includes a novel method of 18F imaging for PET scanning, the method comprising the preparation of conjugates and bioconjugates of biological ligands of interest with heteroaromatic SiFAs. In one embodiment the invention is practiced in the form of a kit.