GLYCOCONJUGUES D'ANTICORPS, PROCEDES DE PRODUCTION ET D'UTILISATION

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专利权人:

NATIONAL RESEARCH COUNCIL OF CANADA

发明人:

GILBERT, MICHEL,SULEA, TRAIAN,JARAMILLO, MARIA,DUROCHER, YVES,ACCHIONE, MAURIZIO

申请号：

CA3082231

公开号：

CA3082231A1

申请日:

2018.11.08

申请国别(地区):

CA

年份:

2019

代理人:

摘要：

The present invention relates to compounds, compositions, and methods are provided for covalently linking a cargo molecule, such as a therapeutic or a diagnostic agent, to a glycan in the Fab region of an antibody. Also provided are methods of modeling and producing antibodies having de novo Fab glycosylation sites. Also provided are antibody carrier conjugates, methods of using the conjugates.

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中国工程科技知识中心

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