GIEFFERS, CHRISTIAN,HILL, OLIVER,THIEMANN, MEINOLF,SCHNYDER, TIM
申请号:
CA3002602
公开号:
CA3002602A1
申请日:
2016.10.24
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
Provided herein are specific CD27 receptor agonist proteins, nucleic acids encoding the same, and methods of treating a subject having a CD27L-associated disease or disorder. The CD27 receptor agonist proteins provided herein comprise three soluble CD27L domains and an Fc fragment. The CD27 receptor agonist proteins are substantially non-aggregating and suitable for therapeutic, diagnostic and/or research applications.