The present invention relates to a method and an apparatus for lipid removal using infrared OPO laser. Specifically, the method and the apparatus can remove fat from a living body in a more energy-efficient, rapid and effective manner by irradiating fat in the living body directly with two infrared lasers having wavelengths of about 2,300 nm and about 1,980 nm, which are generated using a pump laser having a wavelength of about 1,064 nm as a light source.