METALLIC NANOPARTICLE ALONE AND/OR IN COMBINATION AS NOVEL AGENT FOR THE TREATMENT OF UNCONTROLLED ELECTRIC CONDUCTANCE RELATED DISORDERS AND/OR SEIZURE, EPILEPSY & CONVULSIONS.
The present invention relates to pharmaceutical composition/s comprising of at-least one of metallic nanoparticles either alone or in their combinations, more preferably such metallic nanoparticles here may be of gold, silver and zinc nanoparticles more particularly preferred if such composition may also contain at-least one of drugs from the category such as antiseizure, antiepileptic, antioxidants or nutraceuticals or other therapeutic class having potential to be use in such disorders, so that these compositions would be useful in therapeutic or prophylactic treatment as well as the management of pathophysiological or pathological states, arising either due to unregulated or unbalanced or dysregulated electrical conductance such as (but not limited to) mainly convulsions and/or seizures and/or epilepsies etc. The present invention also discloses a more preferable synergistic and potentiating pharmaceutical composition which may be combination of at-least one of metallic nanoparticles with the carbamazepine more specifically to say such preferred metallic nanoparticles here may be gold, silver and zinc nanoparticles as therapeutic or prophylactic treatment for the management of any pathophysiological or pathological states arising due to unregulated or unbalanced or dysregulated type of electric conductance disorders preferably such as convulsions, seizures or epilepsies.La présente invention concerne une(des) composition(s) pharmaceutique(s) comprenant au moins lune parmi des nanoparticules métalliques, soit seules soit sous leurs combinaisons, plus préférablement de telles nanoparticules métalliques peuvent être ici des nanoparticules dor, dargent et de zinc on préfère plus particulièrement si si une telle composition peut également contenir au moins lun des médicaments issus de la catégorie telle que des anti-crises, des antiépileptiques, des antioxydants ou des nutraceutiques ou autre classe thérapeutique ayant la possibilité dêtre utilisé dans de tels trouble