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3- (4-Aminophenyl) -2-furancarboxylic acid derivative and pharmaceutically acceptable salt thereof
专利权人:
大日本住友製薬株式会社
发明人:
藤井 昭仁,新留 和美,右橋 千秋,亀井 稔之,松本 考史,平田 智之
申请号:
JP2011513354
公开号:
JP5877709B2
申请日:
2010.05.12
申请国别(地区):
JP
年份:
2016
代理人:
摘要:
Disclosed is a compound represented by Formula (I) or a pharmaceutically acceptable salt thereof: wherein R 1 is 1: a C 3-8 cycloalkyl C 1-4 alkyl group, 2: a C 7-14 aralkyl group, in which the aryl moiety thereof is optionally substituted with the same or different 1 to 3 groups selected from the group consisting of: (a) halogen, (b) C 1-4 alkyl, which is optionally substituted with 1 to 3 fluorine atoms, (c) C 1-4 alkoxy, which is optionally substituted with 1 to 3 fluorine atoms, and (d) C 1-4 alkylcarbonyl, which is optionally substituted with C 1-4 alkoxy, 3: a five- to ten-membered heteroaryl-C 1-4 alkyl group, in which the heteroaryl moiety thereof is optionally substituted with the same or different 1 to 3 groups selected from the group consisting of: (a) halogen, and (b) C 1-4 alkyl, or 4: a C 6-10 aryl C 2-6 alkenyl group; and R 2 is a cyano group or a nitro group.
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