CELL FOR USE IN IMMUNOTHERAPY WHICH CONTAINS MODIFIED NUCLEIC ACID CONSTRUCT ENCODING WILMS TUMOR GENE PRODUCT OR FRAGMENT THEREOF, METHOD FOR PRODUCING SAID CELL, AND SAID NUCLEIC ACID CONSTRUCT

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专利权人:

RIKEN

发明人:

Fuji, Shin-ichiro,Shimizu, Kanako,Shinga, Jun

申请号：

AU2016204658

公开号：

AU2016204658A1

申请日:

2016.07.07

申请国别(地区):

AU

年份:

2016

代理人:

摘要：

#$%^&*AU2016204658A120160901.pdf#####RK1812/PCT - 40 Abstract A cell of the present invention contains a nucleic acid construct encoding a WT1 gene product or a fragment of the WT1 gene product. The nucleic acid construct contains (i) a 5 region encoding a desired fragment of the WT1 gene product and (ii) only AUG as a functional start codon. The present invention can provide a cell into which the nucleic acid construct is introduced so that an expression level of a WT1 gene product or a fragment of the WT1 gene product is ) remarkably enhanced.

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