PROBLEM TO BE SOLVED: To provide a composition of a pharmaceutical, food and drink, etc., for fundamentally preventing, improving or treating eye disease and neuropathy which are conventionally difficult to treat by finding out a substance having differentiation-inducing activity from stem cells to ectodermal cells.SOLUTION: A differentiation inducer from stem cells to ectodermal cells includes fucoidan as an active ingredient. The ectodermal cell differentiation inducer can efficiently induce the differentiation from the stem cells to ectodermal cells such as constituting cells of eyes, nerve cells, etc., and also can provide a composition of a pharmaceutical, food and drink, etc., for fundamentally preventing, improving or treating eye disease and neuropathy which are conventionally difficult to treat.COPYRIGHT: (C)2014,JPO&INPIT【課題】幹細胞から外胚葉系細胞への分化誘導活性を有する物質を見出し、これまで治療が困難であった眼疾患や神経疾患を根本的に予防、改善又は治療するための医薬品や飲食品等の組成物を提供する。【解決手段】フコイダンを有効成分として含有する、幹細胞から外胚葉系細胞への分化誘導剤である。外胚葉系細胞分化誘導剤は、幹細胞から眼の構成細胞や神経細胞等の外胚葉系細胞を効率的に分化誘導でき、これまで治療が困難であった眼疾患や神経疾患を根本的に予防、改善又は治療するための医薬品や飲食品等の組成物を提供することができる。【選択図】図1