DOMINGUEZ, ESTEBAN,GUO, DEQI,MADER, MARY MARGARET,NGUYEN, ANH-QUAN HANNAH,DEL PRADO, MIRIAM FILADELFA,RICHETT, MICHAEL ENRICO,RODRIGUEZ, MICHAEL JOHN,YIP, YVONNE YEE MAI,YU, KUO-LONG
申请号:
CA2994428
公开号:
CA2994428A1
申请日:
2016.08.22
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The present invention relates to compounds that inhibit activity of the histone lysine methyltransferase, Enhancer of Zeste Homolog 2 (EZH2), pharmaceutical compositions comprising the compounds, and methods of using the compounds to treat cancer, such as hematologic and solid tumors.