BI, YINGZHI,毕映枝,畢映枝,CARSON, KENNETH GORDON,卡尔森肯尼士高登,卡爾森肯尼士高登,CIANCHETTA, GIOVANNI,钱切达乔伐尼,錢切達喬伐尼,GREEN, MICHAEL ALAN,葛林麦可亚伦,葛林麥可亞倫,KUMI, GODWIN,古米葛德温,古米葛德溫,MAIN, ALAN,曼恩艾伦,曼恩艾倫,ZHANG, YULIAN,张玉莲,張玉蓮,ZI
申请号：
TW102108283
公开号：
TW201341386A
申请日:
2013.03.08
申请国别(地区):
TW
年份:
2013
代理人:
摘要：
Pyrazolo[1,5-a]pyrimidine-based compounds of the formula: are disclosed, wherein R1, R2 and R3 are defined herein. Compositions comprising the compounds and methods of their use to treat, manage and/or prevent diseases and disorders mediated by mediated by adaptor associated kinase 1 activity are also disclosed.本文揭示具有以下化學式之唑並[1,5-a]嘧啶基化合物：其中，本文中定義了R1、R2及R3。本文亦揭示包含該等化合物之組成物及其使用方法，使用方法為治療、管理及/或預防由銜接因子關聯激酶1活性介導之疾病及失調症。
