Methods to prepare penta-1,4-dien-3-ones and substituted cyclohexanones and derivatives with antitumoral and antiparasitic properties, the compounds and their uses
José Agustin Quincoces Suárez,Durvanei Augusto Maria,Daniela Goncales Rando,Clizete Aparecida Sbravate Martins,Paulo Celso Pardi,Pamela Oliveira De Souza
申请号:
US12307669
公开号:
US08859625B2
申请日:
2007.07.06
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention refers to new derivatives of the penta-1,4-dien-3-ones, as well as their processes of preparation. These compounds present strong antitumoral activity and promising antiparasitic action, behaving as almost atoxic by laboratory assays and also by hystopathologic studies. The present invention refers also to a pharmaceutical composition including the referred compounds, method of treatment for cancer and parasitic diseases.