A portable measurement device configured to receive vital sign measurements and wirelessly transmit the vital sign measurements is presented. The transmitted vital sign measurements may be received, in real time, by a computing device that stores a list of patients and pre-programmed alert generation condition for each of the patients. When the vital sign measurements fulfill the alert generation condition, the computing device generates an alert, for example to medical staff tasked with the remote monitoring. One or more of EKG data, pulse oximetry, heart rate, pulse rate, systolic blood pressure, diastolic blood pressure, non-invasive blood pressure, and temperature may be monitored remotely using the inventive concepts.