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架橋ヒアルロン酸組成物及び自己架橋ヒアルロン酸粒子
专利权人:
デンカ株式会社
发明人:
橋本 正道,守川 忠志,宮田 喜明,大野 昭男,高橋 啓,小笠原 大輔,藤井 健治,架間 晃明,竹田 茉利子
申请号:
JP2012530678
公开号:
JP5824455B2
申请日:
2011.08.23
申请国别(地区):
JP
年份:
2015
代理人:
摘要:
The present invention provides a crosslinked hyaluronic acid composition including self-crosslinking hyaluronic acid particles having an equilibrium swelling capacity of 3-fold to 10-fold, and an aqueous solvent, wherein a dry weight of the self-crosslinking hyaluronic acid particles based on the total volume of the crosslinked hyaluronic acid composition is 3 w/v% to 8 w/v%. The crosslinked hyaluronic acid composition of the invention uses self-crosslinking hyaluronic acid particles of which the equilibrium swelling capacity is within the above predetermined range. Accordingly, the viscosity does not sharply increase even if the concentration thereof is increased. Therefore, if the crosslinked hyaluronic acid composition is applied to an injection, it is possible to obtain a sufficient curative effect on knee osteoarthritis even with a small frequency of administration.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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