A problem of the present disclosure is, in one embodiment, to create a hard capsule formulation that includes a pharmaceutical agent or the like whose components deteriorate upon contact with an acid, in which the pharmaceutical agent or the like does not deteriorate due to gastric acid penetrating into the outer shell of the hard capsule. A hard capsule formulation comprising a hard capsule with acid resistance, in which the hard capsule is not treated with enteric coating, and the hard capsule formulation comprises an agent to inhibit invasion of gastric fluid and a pharmaceutical agent in the hard capsule.La présente invention concerne une formulation de capsule dure comprenant une capsule dure résistance à l'acide, la capsule dure n'étant pas traitée avec un enrobage gastro-résistant, et la formulation de capsule dure comprend un agent destiné à inhiber l'invasion de fluide gastrique et un agent pharmaceutique dans la capsule dure.
