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COMPOSICIONES FARMACEUTICAS
- 专利权人:
- ARES TRADING S.A.
- 发明人:
- BJOERN COLIN KAHRS
- 申请号：
- ARP120104793
- 公开号：
- AR089301A1
- 申请日:
- 2012.12.18
- 申请国别(地区):
- AR
- 年份:
- 2014
- 代理人:
- 摘要：
- Pharmaceutical compositions comprising PPAR agonists and Nrf2 Activators and Methods of using combinations of Nrf2 activators of PPAR and agonists to treat diseases such as psoriasis, Asthma, multiple sclerosis, inflammatory bowel disease and arthritis.Claim 1: a PPAR agonist G selected Group of glitazones for use in the treatment of an inflammatory autoimmune disorder and \/ or, where such a PPAR agonist G administered simultaneously or sequentially), separated with Nrf2 Activator isolated, Selected gr Rate of fumaric acid Esters (methyl, bardoxolona Methyl 2 - cyano - 3:12 - dioxooleana - 19 (11) - dien - 28 - oate, cddo, RTA 402), 2 - cyano - 3,12 (11) dioxooleana - 1.9 - dien - 28 - oate acid, 2 - cyano - 3,12 dioxooleana - 1.9 - (11) - (Dien 28 - acid, 1 - [2 cddo) - cyano - 3,12 dioxooleana - 1.9 - (11) - dien - 28 - oil] imidazole (cddo - LM) 2 - cyano - N - methyl - 3 -, 12 - dioxooleana 1.9 (11) - dien - 28 cddo amide (- metilamida, cddo - MA), [(+) - (4BS, 8aR, 10aS) - 10th - ethinyl - 4b, 8.8 - trimethyl - 3.7 - cyclohexanecarboxylic 3,4b, 7,8,8a, 9,10,10a - octahidrofenantren - 2.6 - dicarbonitrilo] (GER - 31), 2 - cyano - 3,12 dioxooleana - 1.9 - (11) - dien - 28 - onitrilo (TP - 225), 3 - 4 - Tert Butyl hydroxyanisole, 2 - 4 - Tert Butyl hydroxyanisole (BHA), butilquinona ter - (TBq), tert butylhydroquinone (TBHQ), 3,5 - di Tert Butyl - 4 - hydroxytoluene (BHT), 2,6 di Tert Butyl - 4 - methylene 2,5-cyclohexadi en - 1 - One (meturo of 2,6 di tert butilquinona, meturo of ethoxyquin, BHT quinone)Esters of gallic acid, curcumin, reservatrol, menadione, cinnamic aldehyde, cinnamic acid esters, esters of caffeic acid, cafestol and kahweol, lycopene, carnosol, sulforafan, oltipraz, 5 - (4 - methoxy phenyl) - 1,2-dithiol-3-thione (ADT), sulfasalazine, 5-aminosalicylic acid (mesalamin (a), 4 - (5 - tioxo - 5H - [1,2] ditiol - 3 - yl) - fenil\u00e9ster 5 - amino acid - 2 - hydroxy benzoic (ATB - 429), allicinAllylisothiocyanate zerumbona, isothiocyanate, Phenet
- 来源网站：
- 中国工程科技知识中心
- 来源网址：
- http://www.ckcest.cn/home/
