LOPASCHUK, GARY, DAVID,VEDERAS, JOHN, C.,DYCK, JASON, R.
申请号:
HK08105963.4
公开号:
HK1111141B
申请日:
2008.05.28
申请国别(地区):
HK
年份:
2016
代理人:
摘要:
The invention provides novel compounds of the Formula (I) that stimulate rates of glucose oxidation in myocardial cells: wherein W, Cyc, p, Y, X, Z, R, R1, R2, R3, R4, I, m and n are as defined for Formula (I) herein. The invention also relates to pharmaceutical compositions comprising compounds capable of stimulation of glucose oxidation, methods for increasing glucose oxidation rates in myocardial cells, and methods of treatment of myocardial ischemia.