Brian A. Zabel,Eugene C. Butcher,Russell K. Pachynski,Justin Monnier
申请号：
US15199476
公开号：
US20170002087A1
申请日:
2016.06.30
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Chemerin is a chemoattractant that selectively directs intra-tumor recruitment of CMKLR1+ cells. Blockade of CCRL2 from binding to chemerin in non-neoplastic tumor cells, e.g. peri-tumor stromal and/or hematopoietic cells allows for redistribution of chemerin into the tumor and enhanced responsiveness against a tumor.
