THE LUDWIG INSTITUTE FOR CANCER RESEARCH;HELSINKI UNIVERSITY LICENSING LTD. OY
发明人:
ALITALO, KARI,JOUKOV, VLADIMIR
申请号：
CA2279554
公开号：
CA2279554C
申请日:
1998.02.02
申请国别(地区):
CA
年份:
2012
代理人:
摘要：
Provided are purified and isolated VEGF-C polypeptides capable of binding toat least one of KDR receptor tyrosine kinase (VEGFR-2) and Flt4 receptortyrosine kinase (VEGFR-3)； analogs of such peptides that have VEGF-C-like orVEGF-like biological activities or that are VEGF or VEGF-C inhibitors；polynucleotides encoding the polypeptides； vectors and host cells that embodythe polynucleotides； pharmaceutical compositions and diagnostic reagentscomprising the polypeptides； and methods of making and using the polypeptides.
