The present invention provides a biomarker for detecting and diagnosing polypoidal choroidal vasculopathy (PCV) of human eyes, including effect levels of hyperhomocysteinemia that are identified, wherein effect levels of hyperhomocysteinemia are highly correlated with PCV of the human eyes. In addition, this invention further provides a method for detecting and diagnosing PCV of the human eyes.本發明提供一種偵測及診斷人類眼部之息肉狀脈絡膜血管病變之生物標記，包括確定高同型半胱氨酸血症的作用程度，其中，該高同型半胱氨酸血症的作用程度與該人類眼部之該息肉狀脈絡膜血管病變高度相關聯。此外，本發明進一步提供一種偵測及診斷人類眼部之息肉狀脈絡膜血管病變的方法。
