A compound for treating a protein kinase-related disease or disorder having a structure of formula (I) wherein L is NR8 or O； R1, R2, R3, R4, R5, R6 and R7 are defined herein. Compounds of formula (I) are useful for inhibition of protein kinases. Methods of using compounds of formula (I), stereoisomers, tautomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.一種治療與蛋白質激酶有關的疾病或病症之化合物，其具有式(I)之結構：其中L係NR8或O；R1、R2、R3、R4、R5、R6及R7係如本文中所定義。式(I)化合物係有用於蛋白質激酶之抑制。本發明亦揭示使用式(I)化合物、其立體異構物、互變異構物及醫藥上可接受之鹽於活體外、原位及活體內診斷、預防或治療哺乳動物細胞中之此等病症或相關病理症狀之方法。
