The present invention provides a silicone rubber-based curable composition with which a silicone rubber having excellent tensile strength and tear strength is obtained, a method for producing a silicone rubber using the silicone rubber-based curable composition, a silicone rubber, a molded article using the silicone rubber, and a tube for medical use formed from the molded article. The silicone rubber-based curable composition of the present invention is characterized in that it includes a vinyl group-containing organopolysiloxane (A), an organohydrogen polysiloxane (B), silica particles (C), a silane coupling agent (D), and platinum or a platinum compound (E).