Polynucleotides encoding tethered interleukin-12 (IL12) polypeptides and uses thereof

• 收藏
• 分享

专利权人:

Inc.;ModernaTX

发明人:

Mishra, Ankita,Frederick, Joshua,Gurumurthy, Sushma

申请号：

AU2018270111

公开号：

AU2018270111A1

申请日:

2018.05.18

申请国别(地区):

AU

年份:

2019

代理人:

摘要：

The present disclosure relates to polynucleotides encoding tethered interleukin-12 (IL-12) polypeptides comprising an IL-12 polypeptide and a membrane domain. The present disclosure also relates to vectors comprising the polynucleotides； host cells comprising the polynucleotides or vectors, polypeptides encoded by the polynucleotides； compositions comprising the polynucleotides, vectors, host cells, or polypeptides and a delivery agent； and uses thereof, including treatment of cancer.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/