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ANTIBODY-DRUG CONJUGATE
专利权人:
Limited;Daiichi Sankyo Company
发明人:
Masuda, Takeshi,Naito, Hiroyuki,Nakada, Takashi,Yoshida, Masao,Ashida, Shinji,Miyazaki, Hideki,Kasuya, Yuji,Morita, Koji,Abe, Yuki,Ogitani, Yusuke
申请号:
AU2018200308
公开号:
AU2018200308B2
申请日:
2018.01.12
申请国别(地区):
AU
年份:
2019
代理人:
摘要:
#$%^&*AU2018200308B220191107.pdf#####Abstract As an antitumor drug which is excellent in terms of antitumor effect and safety, there is provided an antibody-drug conjugate in which an antitumor compound represented by the following formula is conjugated to an antibody via a linker having a structure represented by the following formula: -L'-L 2LP-NH-(CH2)ni-La-Lb-Lc- wherein the antibody is connected to the terminal of L', and the antitumor compound is connected to the terminal of Lc with the nitrogen atom of the amino group at position 1 as a connecting position.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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