INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION
发明人:
WILKES, DAVID S.,KLEMSZ, MICHAEL J.
申请号：
CA2965211
公开号：
CA2965211C
申请日:
2007.01.13
申请国别(地区):
CA
年份:
2020
代理人:
摘要：
The present invention relates to treatment of medical conditions that involve an autoimmune response to connective tissue such as collagen found in organs such as the lung. Specifically disclosed is a composition comprising Type V collagen or antigenic component thereof for the treatment of pulmonary disease, such as Idiopathic Pulmonary Fibrosis, Adult Respiratory Distress Syndrome, Acute Respiratory Distress Syndrome, secondary collagen vascular disease and any form of fibrotic lung disease, in a patient having autoimmunity to Type V collagen present in a lung. In some embodiments, the composition may further comprise cyclosporine. The composition may be used for oral feeding, intrapulmonary instillation, inhalation, subcutaneous injection, or intravenous injection.
