DIN BELLE, DAVID,HOLM, PATRIK,KARLJALAINEN, ARTO,TOLVANEN, ARTO,WOHLFAHRT, GERD,RUMMAKKO, PETTERI
申请号：
NZ58243208
公开号：
NZ582432A
申请日:
2008.07.18
申请国别(地区):
NZ
年份:
2012
代理人:
摘要：
Disclosed are dihydrobenzo-dioxin compounds represented by general formula (I), or pharmaceutically acceptable salts or esters thereof. Examples of the compounds of formula (I) include 1-(2,3-dihydrobenzo[ 1,4 ]dioxin-2-ylmethyl)-5-phenyl-l ,2,3 ,6-tetrahydropyridine, 1-(2,3-dihydrobenzo[ 1,4 ]dioxin-2-ylmethyl)-3-phenylpiperidine and 1-(2,3-dihydrobenzo[I,4 ]dioxin-2-ylmethyl)-3-(2-methoxyphenyl)piperidine, 3-( 4-chlorophenyl)-I-(2,3-dihydrobenzo[ 1,4 ] dioxin-2-ulmethyl)piperidine, The compounds of formula (I) are useful in treating a mental disorder propagated by stress, Parkinsons disease, depression, schizophrenia, attention deficit hyperactivity disorder, post-traumatic stress disorder, obsessive compulsive disorder, Tourettes syndrome, blepharospasm or other focal dystonias, temporal lobe epilepsy with psychosis, a drug-induced psychosis, Huntingtons disease, a disorder caused by fluctuation of the levels of sex hormones, panic disorder, Alzheimers disease or mild cognitive impairment.
