Described is a sheath removal mechanism (1) for removing a protective needle sheath (2) from an injection needle (3) of a syringe (4) in a drug delivery device (5). The sheath removal mechanism (1) comprises a cap (6) adapted to cover a distal end of a drug delivery device (5) and adapted to engage the protective needle sheath (2), and at least one rotatable cam (7) adapted to move the cap (6) in a distal direction (D) away from the syringe (4) when rotated from a first rotational position (P1) towards a second rotational position (P2).本發明係一種護套移除機構(1),用於在一藥品輸送裝置(5)中由一注射器(4)之注射針(3)移除一保護針護套(2)。該護套移除機構(1)包含:一蓋子(6),其適於蓋住一藥品輸送裝置(5)之一遠側端,且適於嚙合該保護針護套(2);及至少一可旋轉凸輪(7),其適於當由一第一旋轉位置(P1)旋轉朝一第二旋轉位置(P2)時,在一遠側方向(D)中移動該蓋子(6)遠離該注射器(4)。