Marc F. Pelletier,Paul Robert McGuirk,George William Farr,Steven Williams
申请号:
US15034543
公开号:
US09949991B2
申请日:
2014.11.06
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to the use of selective aquaporin inhibitors, e.g., of aquaporin-4 or aquaporin-2, e.g., certain phenylbenzamide compounds, for the prophylaxis, treatment and control of aquaporin-mediated conditions, e.g., glioblastoma and ovarian hyperstimulation syndrome. The invention provides, inter alia, methods of treating or controlling a disease condition mediated by an aquaporin, e.g., diseases or conditions of water imbalance and other diseases.